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We aimed to investigate whether 1-deoxynojirimycin (DNJ) has effects on cholesterol efflux in adipocytes and modulates ABCA1 expression in high fat fed mice. Fully differentiated 3T3-L1 adipocytes were tested for the cytotoxicity of DNJ and cholesterol efflux into apoA1/HDL was then assessed. ABCA1 protein levels and nuclear abundance of LXRα were measured after the treatment of DNJ in differentiated...
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