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Tumor Targeting
In article number 2305215, Ling Peng, Jing Ma, and co‐workers developed a self‐assembling dendrimer nanosystem decorated with an anti‐PD‐L1 antibody to deliver an siRNA targeting pyruvate dehydrogenase kinase 1 for simultaneously inhibiting glycolysis and immune escape, hence blocking tumor growth and metastasis. This study highlights the potential of self‐assembling dendrimer platform...
Breast cancer is the most frequent malignancy affecting women, yet current therapeutic strategies remain ineffective for patients with late‐stage or metastatic disease. Here an effective strategy is reported for treating metastatic breast cancer. Specifically, a self‐assembling dendrimer nanosystem decorated with an antibody against programmed cell death ligand 1 (PD‐L1) is established for delivering...
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