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The human skin penetration of N-nitroso-N-methyldodecylamine (NDOMA) from isopropyl myristate (IPM) and two vehicles representative of cosmetic/personal care formulations was determined in vitro. When applied as an infinite dose in IPM (1 μg/μl) the average total absorption over 48 hr was 0.10 ± 0.01% of the applied dose (all data are expressed as means ± SE). When applied as a finite dose in a...
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