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It is thought that Shine–Dalgarno-like sequences, which exhibit complementarity to the nucleotide sequences at the 3′-end of 18S rRNA, are not present in eukaryotic mRNAs. However, complementary sequences consisting of more than 5 nucleotides to the 3′-end of 18S rRNA, i.e., a CR sequence, are present at −17 to −32 upstream from the initiation codon AUG in 18 mRNAs involved in protein synthesis except...
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