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Triacylglycerol (TAG) accumulation mechanisms under stress have been intensively investigated in recent years in microalgae and efforts aiming to increase TAG synthesis have been made through gene engineering. However, only a few studies report the contribution of lipid breakdown to TAG accumulation in microalgae. In this study, a putative TAG lipase OmTGL in P. tricornutum was identified based on...
The tricarboxylic acid (TCA) cycle is a key metabolic pathway that unifies carbohydrate, lipid and protein metabolism. In Phaeodactylum tricornutum, accumulation of triacylglycerols (TAGs) under nitrogen stress is a consequence of re-allocation of carbon mainly from the intermediates of TCA cycle. Oxaloacetate, an intermediate of the TCA cycle, can flux out of the cycle by the decarboxylation enzyme...
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