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Corticotropin-releasing factor (CRF) is released in response to various types of stressors and mediates endocrine, autonomic, immune, and behavioral responses to stress through interaction with CRF 1 and CRF 2 receptors. To investigate the role of CRF 1 receptors in physiological responses to surgical stress, we analyzed the effects of two different non-peptide selective CRF...
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