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This paper focuses on a comparative study of the column classification system based on the quantitative structure-retention relationships (QSRR method) and column performance in real biomedical analysis. The assay was carried out for the LC separation of moclobemide and its metabolites in human plasma, using a set of 24 stationary phases. The QSRR models established for the studied stationary phases...
In this paper a comparative study of RP-LC column selectivity as obtained by the classification method of the Katholieke Universiteit Leuven (KUL method) and the selectivity obtained in real pharmaceutical analysis is reported. The separation of caffeine and its respective impurities was performed on 35 brands of stationary phases in accordance with the method prescribed in the European Pharmacopoeia...
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