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The stability of selenium-containing proteins in human serum was investigated by size-exclusion chromatography–ICP-MS under non-denaturating conditions. The peak characteristic to glutathione peroxidase (GSHPx) (tetramer) was the most affected; peaks of the GSHPx monomer and of selenite were found to appear with time. No trace of selenite was present in fresh samples, which suggest that the presence...
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