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The brain‐specific Ras/Rap‐GTPase activating protein (SynGAP) is a prime candidate linking N‐methyl‐d‐aspartate receptors to the regulation of the ERK/MAP kinase signalling cascade, suggested to be essential for experience‐dependent synaptic plasticity. Here, we evaluated the behavioural phenotype of SynGAP heterozygous knockout mice (SG+/−), expressing roughly half the normal levels of SynGAP. In...
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