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Background
Humanized 3F8‐bispecific antibody (hu3F8‐BsAb) using the IgG(L)‐scFv format (where scFv is single‐chain variable fragment), where the anti‐CD3 huOKT3 scFv is fused with the carboxyl end of the hu3F8 light chain, has potent antitumor cytotoxicity against GD2(+) tumors. To overcome the insufficient number and function of T cells in cancer patients, they can be rejuvenated and expanded ex...
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