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European and US guidelines suggest that all patients with dementia should have brain imaging performed as part of the diagnostic work-up. Whilst computer tomography (CT) may be sufficient to exclude the majority of ‘treatable causes’ such as tumours or other mass lesions, magnetic resonance imaging (MRI) allows for a much more detailed assessment of brain structure and white-matter integrity, may...
This study explores the diagnostic utility of atrophy rates of the cingulate gyrus, its subdivisions and the hippocampus in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). Regions were manually outlined on MR images of a group of pathologically or genetically confirmed patients with AD (n=19), FTLD (n=8) and age-matched controls (n=11). Mean (S.D.) atrophy rates (%year −1...
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