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We previously showed that approximately 60% of B chronic lymphocytic leukaemia (B‐CLL) cells express surface CD180, an orphan receptor of the Toll‐like receptor family. Here we investigated the ability of anti‐CD180 monoclonal antibody (mAb) to induce activation, cell cycling, survival and signalling in B‐CLL cells and normal B cells. Upon addition of anti‐CD180 mAb, alone or in combination with anti‐CD40...
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