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BackgroundThe event‐free survival of childhood acute lymphoblastic leukemia (ALL) has been reported to be superior when oral methotrexate (MTX) and 6‐mercaptopurine (6MP) maintenance therapy (MT) is administered in the evening compared to the morning.
ProcedureIn the ALL92 MT study we prospectively registered the intake of MTX/6MP. The registration was done when blood samples for erythrocyte MTX/6MP...
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