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Nectin-4 is a Ca2+-independent immunoglobulin-like cell adhesion molecule which has diverse functions in cell–cell adhesion via homophilic and heterophilic interactions. Cell–cell adhesive processes are central to cell polarization, differentiation, proliferation, survival and movement. Here we report that Nectin-4 is substantially overexpressed in gallbladder cancer (GBC), the most common biliary...
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