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The tomato resistance protein Sw‐5b differs from the classical coiled‐coil nucleotide‐binding leucine‐rich repeat (CC‐NB‐LRR) resistance proteins by having an extra N‐terminal domain (NTD). To understand how NTD, CC and NB‐LRR regulate autoinhibition and activation of Sw‐5b, we dissected the function(s) of each domain.
When viral elicitor was absent, Sw‐5b LRR suppressed the central NB‐ARC to...
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