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The slowly activating delayed rectifier K + channels (I Ks ) are one of the main pharmacological targets for development of drugs against cardiovascular diseases. Cardiac I Ks consists of KCNQ1 plus KCNE1 subunits. Ginsenoside, one of the active ingredient of Panax ginseng, enhances cardiac I Ks currents. However, little is known about the molecular mechanisms of how...
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