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We have developed two CMOS devices to demonstrate the use of CMOS technology for neural imaging and interfacing with the aim of studying the functions of the brain at the molecular level. In this work, we discuss the design, packaging, and implementation of a compact, single device imaging system for imaging inside the mouse brain. We show that the device is capable of imaging and measuring fluorophore...
It is important for diagnosis of glaucoma to grasp 3-D structure of an optic nerve head (ONH). The quantitative 3-D reconstruction of the ONH is required for the diagnosis. We propose a technique to obtain the depth value from stereo image pair of a retinal fundus for the 3-D reconstruction of the ONH. Our technique mainly consists of four steps: (1) cutout of the ONH region from the fundus images,...
We have developed a computer-aided diagnosis system (CAD) to detect abnormalities in fundus images. In Japan, ophthalmologists usually detect hypertensive changes by identifying arteriolar narrowing and focal arteriolar narrowing. The purpose of this study is to develop an automated method for detecting arteriolar narrowing and focal arteriolar narrowing on fundus images. The blood vessel candidates...
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