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We previously provided evidence supporting the existence of a novel leptin‐independent body weight homeostat (“the gravitostat”) that senses body weight and then initiates a homeostatic feed‐back regulation of body weight. We, herein, hypothesize that this feed‐back regulation involves a CNS mechanism. To identify populations of neurones of importance for the putative feed‐back signal induced by increased...
The gravitostat is a novel homeostatic body weight‐regulating mechanism, mostly studied in mice, and recently confirmed in obese humans. In the present study, we explored the effect of weight loading on metabolic outcomes, meal patterns and parameters linked to energy expenditure in both obese and lean rats. Diet‐induced obese (DIO) and lean rats were implanted with capsules weighing either 15% of...
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