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MicroRNAs mainly inhibit coding genes and long non-coding RNA expression. Here, we report that hsa-miR-125b and oncogene SIRT7/oncogenic long non-coding RNA MALAT1 were inversely expressed in bladder cancer. Hsa-miR-125b mimic down-regulated, whereas hsa-miR-125b inhibitor up-regulated the expression of SIRT7 and MALAT1. Binding sites were confirmed between hsa-miR-125b and SIRT7/MALAT1. Up-regulation...
Background and ObjectivesLong intergenic non‐coding RNAs (lincRNAs) are a class of non‐coding RNAs that regulate gene expression via chromatin reprogramming. Taurine Up‐regulated Gene 1 (TUG1) is a lincRNA that is associated with chromatin‐modifying complexes and plays roles in gene regulation. In this study, we determined the expression patterns of TUG1 and the cell proliferation inhibition and apoptosis...
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