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Investigating co-regulation pattern of a group (or cluster) of genes is widely used to explore the topological and biological properties of co-expression network in a specific phenotype condition. Recent approaches go one step beyond and look for change in co-expression patterns in a pair of phenotype conditions during a disease progression. Here we develop a novel multi-objective framework to identify...
MicroRNAs (miRNAs) are a class of small noncoding RNAs that are known to have critical functions across various biological processes. Simultaneous activities of multiple miRNAs can be monitored from their expression profiles under various conditions. We often build up coexpression networks from such profiles. Unfortunately, due to the change of experimental setups (or conditions), the expression profiles...
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