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This study aims to compare and determine the optimum extraction and separation process of the total flavonoids from Scutellaria barbata. The total flavonoids from S. barbata were extracted with an l-arginine solution, methanol, ethyl acetate, and n-butanol. The activities and toxicity of different extracts on HepG2 and L-O2 cells were measured by MTT assay. The TLC method revealed in the sample chromatograms...
Postoperative cognitive dysfunction (POCD) is a subtle cognitive dysfunction, especially memory impairment for weeks or months after surgery. The underlying pathophysiological mechanism of POCD is still unclear. The aim of this study was to exploratively investigate the potential mechanism of POCD by identifying the differences among metabolic profiles of control rats, POCD and no-POCD rats after...
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