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Cell Tracking
In article number 2207626, Jeff W.M. Bulte, Chao Wang, and Ali Shakeri‐Zadeh review the occasional adverse effects encountered with magnetic labeling of cells for in vivo cell tracking using magnetic resonance imaging (MRI) and magnetic particle imaging. Mesenchymal stem cells (MSCs) are abundant in mannose residues on their cell membrane. Using mannose‐sensitive chemical exchange saturation...
Superparamagnetic iron oxide (SPIO)‐labeling of cells has been applied for magnetic resonance imaging (MRI) cell tracking for over 30 years, having resulted in a dozen or so clinical trials. SPIO nanoparticles are biodegradable and can be broken down into elemental iron, and hence the tolerance of cells to magnetic labeling has been overall high. Over the years, however, single reports have accumulated...
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