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Zwei in einem: Die Kombination von zwei Salen‐TiO‐Einheiten in einem einzigen Molekül ermöglicht die enantioselektive Cyanierung von Aldehyden zur Bildung von enantiomerenangereicherten natürlichen oder nichtnatürlichen Cyanhydrinen mit Umsatzzahlen von 1960 bis 172 000 und bis 97 % ee (siehe Schema). Einige der Cyanhydrine sind Schlüsselintermediate in der Synthese von chiralen Pharmazeutika und...
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