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ObjectivesInvestigate the role of the epithelial–mesenchymal interaction of keratocystic odontogenic tumor (KCOT) in influencing osteoclastogenesis.
Materials and MethodsFibroblasts isolated from KCOT fibrous capsule and normal gingival mucosa were, respectively, co‐cultured with human immortalized oral epithelial cells (HIOECs), and the supernatant was collected to make conditioned medium, in which...
Oral Diseases (2012)
Objectives: To investigate the growth characteristics and effects on osteoclastogenesis in fibroblasts isolated from keratocystic odontogenic tumor (KCOT) fibrous capsule.
Materials and Methods: Fibroblasts isolated from KCOT fibrous capsule and normal gingival mucosa were cultured in vitro. Their colony‐forming units and proliferative activity were investigated, and the osteoclastogenic...
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