Search results for: Yi Yan

Items from 1 to 20 out of 500 results

article

Extremely Large Anomalous Hall Conductivity and Unusual Axial Diamagnetism in a Quasi‐1D Dirac Material La₃MgBi₅

Zhe‐Kai Yi, Zhen‐Feng Ouyang, Peng‐Jie Guo, Hui Liang, more

Advanced Materials > 36 > 36 > n/a - n/a

Anomalous Hall effect (AHE), one of the most important electronic transport phenomena, generally appears in ferromagnetic materials but is rare in materials without magnetic elements. Here, a study of La₃MgBi₅ is presented, whose band structure carries multitype Dirac fermions. Although magnetic elements are absent in La₃MgBi₅, the signals of AHE can be observed. In particular, the anomalous Hall...

article

Self‐Assembled PD‐L1 Downregulator to Boost Photodynamic Activated Tumor Immunotherapy Through CDK5 Inhibition

Bai‐Xue Yu, Yi‐Bin Liu, Xia‐Yun Chen, Wei Zhang, more

Small > 20 > 33 > n/a - n/a

The immunosuppressive characteristics and acquired immune resistance can restrain the therapy‐initiated anti‐tumor immunity. In this work, an antibody free programmed death receptor ligand 1 (PD‐L1) downregulator (designated as CeSe) is fabricated to boost photodynamic activated immunotherapy through cyclin‐dependent kinase 5 (CDK5) inhibition. Among which, FDA approved photosensitizer of chlorin...

article

Identification and immune analysis of antimicrobial peptides from the cigarette beetle (Lasioderma serricorne)

Yue Zhang, Yi Yan, Guy Smagghe, Hong Yang, more

Insect Science > 31 > 4 > 1121 - 1134

Antimicrobial peptides (AMPs) in insects are endogenous peptides that are effector components of the innate defense system of the insect. AMPs may serve as antimicrobial agents because of their small molecular weight and broad‐spectrum antimicrobial activity. In this study, we performed transcriptome analysis of cigarette beetle (Lasioderma serricorne) larvae, parasitized by the ectoparasitic wasp,...

article

Disruption of microRNA pathway core genes inhibits molting and reproduction of the cigarette beetle, Lasioderma serricorne

Yi Yan, De‐Qian Liu, Can Li, Wen‐Jia Yang, more

Pest Management Science > 80 > 9 > 4543 - 4552

BACKGROUND MicroRNA (miRNA) pathway genes have been widely reported to participate in several physiological events in insect lifecycles. The cigarette beetle Lasioderma serricorne is an economically important storage pest worldwide. However, the functions of miRNA pathway genes in L. serricorne remain to be clarified. Herein, we investigated the function of molting and reproduction of the miRNA pathway...

article

Tumor Homing Chimeric Peptide Rhomboids to Improve Photodynamic Performance by Inhibiting Therapy‐Upregulated Cyclooxygenase‐2

Wei Zhang, Bai‐Xue Yu, Xia‐Yun Chen, Meng‐Yi Yan, more

Small > 20 > 28 > n/a - n/a

Negative therapeutic feedback of inflammation would extensively attenuate the antitumor effect of photodynamic therapy (PDT). In this work, tumor homing chimeric peptide rhomboids (designated as NP‐Mel) are fabricated to improve photodynamic performance by inhibiting PDT‐upregulated cyclooxygenase‐2 (COX‐2). The hydrophobic photosensitizer of protoporphyrin IX (PpIX) and palmitic acid are conjugated...

article

Intraoperative AI‐assisted early prediction of parathyroid and ischemia alert in endoscopic thyroid surgery

Bo Wang, Jia‐Fan Yu, Si‐Ying Lin, Yi‐Jian Li, more

Head & Neck > 46 > 8 > 1975 - 1987

Background The preservation of parathyroid glands is crucial in endoscopic thyroid surgery to prevent hypocalcemia and related complications. However, current methods for identifying and protecting these glands have limitations. We propose a novel technique that has the potential to improve the safety and efficacy of endoscopic thyroid surgery. Purpose Our study aims to develop a deep learning...

article

HCN channels in the lateral habenula regulate pain and comorbid depressive‐like behaviors in mice

Xue‐zhong Cao, Meng‐ye Zhu, Gang Xu, Fan Li, more

CNS Neuroscience & Therapeutics > 30 > 7 > n/a - n/a

Aims Comorbid anxiodepressive‐like symptoms (CADS) in chronic pain are closely related to the overactivation of the lateral habenula (LHb). Hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels have been implicated to play a key role in regulating neuronal excitability. However, the role of HCN channels in the LHb during CADS has not yet been characterized. This study aimed to investigate...

article

The volatile organic compounds generated from the Maillard reaction between l‐ascorbic acid and l‐cysteine in hot compressed water

Liang Feng, Yan Yang, Ya‐ting Xie, Wen‐yi Yan, more

Journal of the Science of Food and Agriculture > 104 > 10 > 5764 - 5775

BACKGROUND Hot compressed water (HCW), also known as subcritical water (SCW), refers to high‐temperature compressed water in a special physical and chemical state. It is an emerging technology for natural product extraction. The volatile organic compounds (VOCs) generated from the Maillard reaction between l‐ascorbic acid (ASA) and l‐cysteine (Cys) have attracted significant interest in the flavor...

article

Chimeric Peptide‐Engineered Self‐Delivery Nanomedicine for Photodynamic‐Triggered Breast Cancer Immunotherapy by Macrophage Polarization

Yi‐Bin Liu, Xia‐Yun Chen, Bai‐Xue Yu, Yi Cen, more

Small > 20 > 22 > n/a - n/a

A systemic treatment strategy is urgently demanded to suppress the rapid growth and easy metastasis characteristics of breast cancer. In this work, a chimeric peptide‐engineered self‐delivery nanomedicine (designated as ChiP‐CeR) for photodynamic‐triggered breast cancer immunotherapy by macrophage polarization. Among these, ChiP‐CeR is composed of the photosensitizer of chlorine e6 (Ce6) and the TLR7/8...

article

Palynological and macroscopic characters evidence infer the evolutionary history and insight into pollination adaptation in Impatiens (Balsaminaceae)

Yong‐Xiu Song, Tian Hu, Shuai Peng, Yi‐Yan Cong, more

Journal of Systematics and Evolution > 62 > 3 > 403 - 420

The genus Impatiens comprises more than 1000 species and displays enormous morphological diversity. As a taxon that is notoriously difficult to classify morphologically, the taxonomic significance of pollen morphology has been discussed in previous studies. However, there was only limited study on the evolution of palynological and macroscopic character in this genus before. In this paper, we observed...

article

Impacts of climate change and host plant availability on the potential distribution of Bradysia odoriphaga (Diptera: Sciaridae) in China

Lixia Xie, Xinran Wu, Xue Li, Menglei Chen, more

Pest Management Science > 80 > 6 > 2724 - 2737

BACKGROUND Chinese chives (Allium tuberosum Rottler ex Sprengel) are favored by consumers because of its delicious taste and unique fragrance. Bradysia odoriphaga (Diptera: Sciaridae) is a main pest that severely harms Chinese chives and other Liliaceae's production. Climate change may change the future distribution of B. odoriphaga in China. In this study, the CLIMEX was employed to project the...

article

Molecular Motor‐Driven Light‐Controlled Logic‐Gated K⁺ Channel for Cancer Cell Apoptosis

Cong Li, Yaqi Wu, Yihang Zhu, Jing Yan, more

Advanced Materials > 36 > 19 > n/a - n/a

Developing artificial ion transport systems, which process complicated information and step‐wise regulate properties, is essential for deeply comprehending the subtle dynamic behaviors of natural channel proteins (NCPs). Here a photo‐controlled logic‐gated K⁺ channel based on single‐chain random heteropolymers containing molecular motors, exhibiting multi‐core processor‐like properties to step‐wise...

article

Impact of deep muscle invasion on nodal status and survival in patients with pT2 esophageal squamous cancer

Cheng‐Yi Yan, Yi‐Min Gu, Gui‐Dong Shi, Qi‐Xin Shang, more

Journal of Surgical Oncology > 129 > 6 > 1056 - 1062

Background Whether T2 esophageal squamous cell carcinoma should be subclassified remains controversial. We aimed to investigate the impact of the depth of muscularis propria invasion on nodal status and survival outcomes. Methods We identified patients with pT2 esophageal squamous cell carcinoma who underwent primary surgery from January 2009 to June 2017. Clinical data were extracted from prospectively...

article

Single‐nanoparticle electrochemical collision for study of the size‐dependent activity of Au nanoparticles during hydrogen evolution reaction

Yi‐Yan Bai

Electroanalysis > 36 > 3 > n/a - n/a

Identifying the intrinsic electrocatalytic activity of an individual nanoparticle is essential to reveal the structure‐activity relations of catalysts. However, it is challenging as the performance of catalysts is typically evaluated with ensembles, providing an elusive averaged response of complex catalyst‐modified electrodes. Herein, a single‐nanoparticle electrochemical collision (SNEC)‐based method...

article

Mechanism of KDM5A‐mediated H3K4me3 modification in the osteogenic differentiation of mesenchymal stem cells in steroid‐induced osteonecrosis of the femoral head

Yi Yan, Hao Yan, Zhilong Qiu, Liang Long

International Journal of Rheumatic Diseases > 27 > 3 > n/a - n/a

Objectives Steroid‐induced osteonecrosis of the femoral head (SONFH) is characterized by impaired osteogenesis in bone marrow mesenchymal stem cells (BMSCs). This study investigates the role of lysine‐specific demethylase 5A (KDM5A) in SONFH to identify potential therapeutic targets. Methods Human BMSCs were isolated and characterized for cell surface markers and differentiation capacity. A SONFH...

article

Exercise‐inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue

Hongwei Shi, Xiaojing Hao, Yaqin Sun, Yating Zhao, more

Acta Physiologica > 240 > 3 > n/a - n/a

Aim Exercise can reduce body weight and promote white fat browning, but the underlying mechanisms remain largely unknown. This study investigated the role of fibronectin type III domain‐containing protein 5 (FNDC5)/Irisin, a hormone released from exercising muscle, in the browning of white fat in circulating extracellular vesicles (EVs). Methods Mice were subjected to a 4 weeks of running table...

article

MicroR‐9c‐5p and novel‐mir50 co‐target Akt to regulate Lasioderma serricorne reproduction

Yi Yan, Dong‐Dong Qin, Hong Yang, Kang‐Kang Xu, more

Insect Science > 31 > 1 > 106 - 118

High fecundity is a common characteristic of insect pests which increases the difficulty of population control. Serine/threonine kinase Akt is an indispensable component of the insulin signaling pathway. Silencing of LsAkt severely hinders reproduction in Lasioderma serricorne, a stored product insect pest. However, the post‐transcriptional pathway of LsAkt in L. serricorne remains unknown. This study...

article

Quantum Phase Transitions of Interlayer Excitons in van der Waals Heterostructures

Jia-Pei Deng, Zi-Wu Wang, Yu Cui, Yi-Yan Liu, more

physica status solidi (RRL) – Rapid Research Letters > 18 > 2 > n/a - n/a

Quantum phases of interlayer excitons (IXs) in van der Waals heterostructures (vdWHs) play a critical role in determining the fundamental properties of these structures. However, quantum phase transitions between free state and self‐trapped state of IXs remain poorly understood. Herein, the physical pictures for quantum transitions of IXs stemming from the IX–interface optical phonon coupling are...

article

PHR1 involved in the regulation of low phosphate‐induced leaf senescence by modulating phosphorus homeostasis in Arabidopsis

Jian‐Feng Zhang, You‐Yi Wang, Le He, Jing‐Yi Yan, more

Plant, Cell & Environment > 47 > 3 > 799 - 816

Phosphorus (P) is a crucial macronutrient for plant growth, development, and reproduction. The effects of low P (LP) stress on leaf senescence and the role of PHR1 in LP‐induced leaf senescence are still unknown. Here, we report that PHR1 plays a crucial role in LP‐induced leaf senescence, showing delayed leaf senescence in phr1 mutant and accelerated leaf senescence in 35S:PHR1 transgenic Arabidopsis...

article

Thin‐Film Transistors for Integrated Circuits: Fundamentals and Recent Progress

Anzhi Yan, Chunlin Wang, Jianlan Yan, Zhenze Wang, more

Advanced Functional Materials > 34 > 3 > n/a - n/a

High‐performance thin‐film transistors (TFTs) integrated circuits (ICs) have become increasingly necessary to meet the emerging demands such as healthcare, edge computing, and the Internet of Things, etc. This article aims to point out the potential development trends and bottlenecks of TFT ICs, enhancing their performance in terms of electronic performance, stability, consistency, CMOS design, and...

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INFONA - science communication portal

Search results for: Yi Yan

Extremely Large Anomalous Hall Conductivity and Unusual Axial Diamagnetism in a Quasi‐1D Dirac Material La₃MgBi₅

Self‐Assembled PD‐L1 Downregulator to Boost Photodynamic Activated Tumor Immunotherapy Through CDK5 Inhibition

Identification and immune analysis of antimicrobial peptides from the cigarette beetle (Lasioderma serricorne)

Disruption of microRNA pathway core genes inhibits molting and reproduction of the cigarette beetle, Lasioderma serricorne

Tumor Homing Chimeric Peptide Rhomboids to Improve Photodynamic Performance by Inhibiting Therapy‐Upregulated Cyclooxygenase‐2

Intraoperative AI‐assisted early prediction of parathyroid and ischemia alert in endoscopic thyroid surgery

HCN channels in the lateral habenula regulate pain and comorbid depressive‐like behaviors in mice

The volatile organic compounds generated from the Maillard reaction between l‐ascorbic acid and l‐cysteine in hot compressed water

Chimeric Peptide‐Engineered Self‐Delivery Nanomedicine for Photodynamic‐Triggered Breast Cancer Immunotherapy by Macrophage Polarization

Palynological and macroscopic characters evidence infer the evolutionary history and insight into pollination adaptation in Impatiens (Balsaminaceae)

Impacts of climate change and host plant availability on the potential distribution of Bradysia odoriphaga (Diptera: Sciaridae) in China

Molecular Motor‐Driven Light‐Controlled Logic‐Gated K⁺ Channel for Cancer Cell Apoptosis

Impact of deep muscle invasion on nodal status and survival in patients with pT2 esophageal squamous cancer

Single‐nanoparticle electrochemical collision for study of the size‐dependent activity of Au nanoparticles during hydrogen evolution reaction

Mechanism of KDM5A‐mediated H3K4me3 modification in the osteogenic differentiation of mesenchymal stem cells in steroid‐induced osteonecrosis of the femoral head

Exercise‐inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue

MicroR‐9c‐5p and novel‐mir50 co‐target Akt to regulate Lasioderma serricorne reproduction

Quantum Phase Transitions of Interlayer Excitons in van der Waals Heterostructures

PHR1 involved in the regulation of low phosphate‐induced leaf senescence by modulating phosphorus homeostasis in Arabidopsis

Thin‐Film Transistors for Integrated Circuits: Fundamentals and Recent Progress

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