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Microcystin-leucine arginine (MC-LR) is produced by cyanobacteria and can accumulate in lungs through blood circulation. However, the effect of MC-LR on lung remains unclear. In this study, we investigated the chronic, low-dose effect of MC-LR on mouse lung tissues and the influence of MC-LR on mouse alveolar type II epithelial cells (ATII cells).MC-LR was orally administered to mice at 0, 1, 10,...
The effects of chronic low-dose exposure to microcystins were preliminarily studied on sperm quality and testicular function in male mice. Microcystin-LR (MC-LR) was orally administered to male mice at 0, 1, 3.2, and 10μg/L for 3 and 6 months. Our preliminary study found in three-month group, sperm quality declined at 3.2 and 10μg/L doses, testosterone dropped at 10μg/L, levels of LH and FSH increased,...
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