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IPF is characterized by fibroblast accumulation, collagen deposition, and ECM remodeling, with myofibroblasts believed to be the effector cell type. Myofibroblasts develop due to EMT of lung alveolar epithelial cells, which can be induced by TGF‐β. M2 macrophages, a macrophage subpopulation, secrete large amounts of TGF‐β. To clarify the relationship between IPF, EMT, TGF‐β, and M2 macrophages, a...
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