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Purpose Dry powders packaged in aluminum foil blisters are an increasingly common dosage form found in inhalation drug products. Filling of inhalation blisters often involves compressing bulk aerated powder into dense compacts. Sealed blisters are conditioned, e.g., by ultrasonic vibration, to loosen the consolidated powder within, to enable ready dispersion to a respirable aerosol when actuated by...
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