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Purpose To evaluate the effect of slow and ultra-rapid freezing on biopsied blastocysts’ DNA integrity. Methods Forty eight mouse blastocysts were biopsied of which 16 were cryopreserved by slowly freezing and 17 by vitrification. Fourteen intact blastocysts were slowly cryopreserved and 24 were vitrified. Eighteen fresh intact blastocysts and fifteen biopsied blastocysts served as controls. The...
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