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Background/purpose
Autofluorescence has become an important factor associated with diagnosis and treatment of many diseases.
Methods
Full thickness skin grafts and scar biopsies were obtained from five volunteers. The normal skin or scar tissue paraffin‐wax sections were stained with HE and the autofluorescence of collagen fibres was viewed under fluorescence microscopy.
Results
In normal skin,...
IgA nephropathy (IgAN) diagnosis remains largely based upon immunohistologic detection of IgA‐ and IgG‐containing glomerular deposits in renal mesangial cells, and little is known about the underlying pathogenic mechanisms. This study examines the putative contribution of B cell types, including the Breg type, to IgAN pathogenesis. Twenty‐four patients with IgAN and proteinuria (Group A: <3.5 g/24 h,...
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