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Cancer Immunotherapy
In article number 2300833, Jingke Fu, Hailong Ma, and co‐workers load STING agonists ADU‐S100 onto magnetic Spirulina platensis (ADU@Fe‐SP). The magnet‐guided Spirulina platensis release O2 at the tumor site through photosynthesis, thereby relieving hypoxia in the tumor microenvironment (TME), which suppresses tumor progression. Furthermore, the released ADU‐S100 activates the...
Immunotherapy is a revolutionary achievement in cancer treatment. However, inadequate immune cells infiltration in tumor microenvironment (TME) always leads to treatment failure. Moreover, hypoxic TME hampers normal functions of immune cells. Here, it is found that hypoxia suppresses the STING signaling and immune cells activation in the work. Remodeling tumor immune microenvironment and relieving...