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Purpose
Interleukin (IL)‐6 plays as a modulator for functions of lymphocytes. Significantly higher level of IL‐6 has been observed in primary orbital tissue cultures of thyroid‐associated ophthalmopathy (TAO) patients compared to those of non‐TAO patients. In the current study, we investigated the issue of whether of how orbital fibroblasts (OFs) from TAO patients significantly secret higher level...
Objective: HD203 is a biosimilar of etanercept, a fusion protein of the ligand-binding portion of the human tumor necrosis factor receptor II linked to the Fc portion of human immunoglobulin G1. Since HD203 is under clinical development, this study was conducted to compare the pharmacokinetics of HD203 with Enbrel ®, the first marketed etanercept. Methods: A double-blind, randomized, single-dose,...
Long days and high temperatures changed the growth habit of the normally determinate lablab bean (Lablab purpureus) plant to indeterminate. The critical daylength for the change was 13 h at 25°C and between 10 and 11 h at 30°C. No change in habit occurred at 20°C in any daylength, indicating the existence of a minimum temperature for the change. Plants of indeterminate growth habit showed an increased...
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