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The change in the physical properties of the lipid bilayer when the substrate is bound by membrane proteins is investigated theoretically. They are very pronounced only for certain protein concentrations and are determined by the size of the zones of distorted structure of the bilayer which surround the free molecules of the receptors and receptor-substrate complexes. The mechanisms of hormone-sensitivity...
Fluctuations in the elasticity of the bilayer accompanying the reaction of binding and dissociation of the substrate with the macromolecules incorporated into the bilayer may contain information on the binding and dissociation rate constants of the substrate by the receptor and also on the size of the zones of distortions of the bilayer around the incorporated macromolecules and their number on the...
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