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Key points
N‐cadherin formed punctate adherens junctions (AJ) along the borders between vascular smooth muscle cells (VSMCs) in the pressurized rat superior cerebellar artery.
The formation of N‐cadherin AJs in the vessel wall depends on the intraluminal pressure and was responsive to treatment with phenylephrine (PE) (10−5 m) and ACh (10−5 m).
N‐cadherin‐coated beads were able to induce clustering...
Key pointsThis study demonstrates rapid and dynamic changes in adhesion and cell elasticity following agonist stimulation that culminate in a remodelled cytoskeleton in vascular smooth muscle.Evidence is presented that the changes in adhesion and elasticity are coordinated and that these variables demonstrate temporal oscillation consisting of three major oscillation components.Eigen‐decomposition...
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