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Organ on Chips
In article number 2214179, Lining Arnold Ju and co‐workers, devised a novel, cost‐effective, and high‐throughput fabrication method for the creation of personalized vein‐chips, employing movable typing stereolithography and organ‐on‐chip technologies. This innovative chip accurately replicates an individual patient's unique anatomy and hemodynamics, thereby facilitating the investigation...
The Vein‐Chip recapitulates CVST Virchow's triad and enables systematic characterization of venous thrombogenesis with respect to fibrin formation and platelet aggregation. Distinct from the arterial setting, platelets universally adhere across the entire CVS Vein‐Chip independent of stenotic geometry and flow disturbance. Intriguingly, fibrin propagates along with the flow direction, but exclusively...
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