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Kinins mediate their cellular effects through B1 (B1R) and B2 (B2R) receptors, and the activation of B2R reduces collagen synthesis in cardiac fibroblasts (CF). However, the question of whether B1R and/or B2R have a role in cardiac myofibroblasts remains unanswered.CF were isolated from neonate rats and myofibroblasts were generated by an 84h treatment with TGF-β1 (CMF). B1R was evaluated by western...
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