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AimsTo compare the time profile of insulin detemir and human insulin concentrations in the interstitial fluid (ISF) of subcutaneous adipose tissue during constant i.v. infusion and to investigate the relationship between the pharmacokinetics of both insulin molecules in plasma and the ISF of subcutaneous adipose tissue.
MethodsDuring a 6‐h hyperinsulinaemic–euglycaemic clamp (plasma glucose level...
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