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The present study investigated the effects of iberiotoxin (IbTx), a peptide toxin blocker of large-conductance Ca 2+ -activated K + (BK Ca ) channels and NS1619, a BK Ca channel opener, on action potential firing of small and medium size afferent neurons from L6 and S1 dorsal root ganglia of adult rats. Application of IbTx (100 nM) reduced whole-cell...
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