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To explore the effect and mechanism of exendin-4 on dexamethasone-induced apoptosis in pancreatic β-cells.Murine MIN6 pancreatic β-cells were treated with dexamethasone (100nmol/l) over 48h following pretreatment with exendin-4 (100nmol/l). Cell viability was determined using an MTT assay. The percentage of apoptotic cells was determined through fluorescence microscopy analysis after Hochest/PI staining...
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