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The 5′ HoxD genes and their paralogs in the HoxD cluster are crucial for normal vertebrate limb development. Mutations in HOXD13 and HOXD13 have been found to cause human limb malformation. Here we describe a two-generation Chinese family with a variant form of mild synpolydactyly.Sequence analysis of HOXD13 gene in a two-generation Chinese family with six individuals.Gene scan and linkage analysis...
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