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Background Previous studies have suggested that antithrombin may be beneficial for treating coagulopathy in patients with severe burns. However, robust evidence for this idea is lacking. We examined the hypothesis that antithrombin may be effective in treating patients with severe burns. Methods We performed propensity score-matched analyses of the nationwide administrative Japanese Diagnosis Procedure...
Background The role of low-dose corticosteroid as an adjunctive treatment for abdominal septic shock remains controversial. Methods We identified refractory septic shock patients who required noradrenaline and at least one of other vasopressor/inotropic (dopamine, dobutamine or vasopressin) following emergency open laparotomy for perforation of the lower intestinal tract between July 2010 and March...
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