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Alkyl gallate, which is known as an antioxidant, intensively inhibited Δ5 and Δ6 desaturation in both rat liver microsomes and an arachidonic acid-producing fungus Mortierella alpina 1S-4. The rat liver microsomal Δ5 and Δ6 desaturates were inhibited by gallic acid esterified with alcohols with various numbers of carbons, suggesting that the necessary structure in an esterified alcohol for the inhibition...
Two forms of cytochrome b 5 have been purified from the microsomes of an arachidonic acid-producing fungus, Mortierella hygrophila IFO 5941, after detergent solubilization. They have monomeric molecular masses of about 16 kDa and 19 kDa. Their absorption spectra are similar to those of mammalian cytochrome b 5 s. Their amino acid compositions show some similarity to those of mammalian...
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