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Shiga toxin type 2, a major virulence factor produced by the Shiga toxin–producing Escherichia coli, is a potential toxin agent of bioterrorism. In this study, iodine-125 (125I) was used as an indicator to describe the in vivo Stx2 biodistribution profile. The rats were injected intravenously (i.v.) with 125I-Stx2 at three doses of 5.1–127.5 μg/kg body weight. Stx2 had a short distribution half-life...
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