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An increase in IgE antibody levels to inhalant allergens is associated with an increased likelihood of wheezing. The role of allergen-specific IgG and IgG4 in relation to wheezing is yet to be determined.We sought to investigate whether Fel d 1–specific IgG and IgG4 antibodies modify the association between cat allergen–specific IgE and childhood wheezing.We used data from 2 population-based birth...
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