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In the higher eukaryotic nucleolus, fibrillar centers (FCs), the dense fibrillar components (DFCs), and the granular components (GCs) are functional domains structurally relatively well‐defined by electron microscopy (EM). However, ultrastructural alterations in FC, DFC, and GC during the cell cycle and their associated cellular functions are still largely unclear. Based on synchronized HeLa cells,...
Radon exposure has been linked to lung carcinogenesis in both human and animal studies. The identification of sequential changes in DNA methylation during tumour progression and the elucidation of their interplay with genetic changes will broaden our molecular understanding of this disease. Rats were exposed to 120 or 400 working level months (WLM) of radon, lung pathological changes were examined...
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