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The aim of this study was to explore potential transport mechanisms of cetirizine enantiomers across Caco‐2 cells. Cetirizine displayed polarized transport at concentrations ranging from 4.0 to 80.0 μM, with the permeability in the secretory direction being 1.4‐ to 4.0‐fold higher than that in the absorptive direction. Cetirizine enantiomers were transported distinctively different from each other...
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