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PURPOSE We have reported that long-term topical steroid augments contact hypersensitivity reaction in mice. Therefore, we studied the mechanism of down-regulation of this steroid induced augmentation of contact hypersensitivity reaction. METHOD Balb/c mice were applied on the flank skin with 50 μl of Diflucortron solution in ethanol on alternate day for 9 times. On day 14 when mice received 7th...
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