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The purpose of this study was to examine the biodistribution of the photosensitizing drug, mesochlorin e6 monoethylenediamine (Mce6), and the antineoplastic agent, adriamycin (ADR), as well as their N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer conjugates in female nu/nu athymic mice bearing human ovarian carcinoma OVCAR-3 xenografts. The levels of Mce6 and HPMA copolymer-bound Mce6 in tissues...
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