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We investigate distributed Model Predictive Control (MPC) to damp wide-area electromechanical oscillations. Our distributed MPC schemes are derived from and compared with a fully centralized MPC scheme proposed in a previous publication. Based on simulations carried out using a 16-generator, 70-bus, two-area test power system, we show that simple coordination schemes based on additional local measurements'...
Emerging next-generation sequencing (NGS) technology potentially resolves many issues that prevent widespread clinical use of gene expression microarrays. However, the number of publicly available NGS datasets is still smaller than that of microarrays. This paper explores the possibilities for combining information from both microarray and NGS gene expression datasets for the discovery of differentially...
This paper introduces a new Model Predictive Control (MPC) scheme to damp wide-area electromechanical oscillations. The proposed MPC controller, based on a linearized discrete-time state space model, calculates the optimal input sequence for local damping controllers over a chosen time horizon by solving a quadratic programming problem. Local controllers considered include: Power Systems Stabilizers...
We developed a scalable distributed computing system using the Berkeley Open Interface for Network Computing (BOINC) to align next-generation sequencing (NGS) data quickly and accurately. NGS technology is emerging as a promising platform for gene expression analysis due to its high sensitivity compared to traditional genomic microarray technology. However, despite the benefits, NGS datasets can be...
The recent and imminent launch of the SMOS and Aquarius satellites carrying microwave L-band radiometers provides an opportunity to map Sea Surface Salinity (SSS) globally with an expected error <; 0.2 psu. However, the accuracy of retrieved SSS depends critically on brightness temperature (Tb) corrections for sea surface roughness (SSR) effects. This paper assesses the performance of representative...
Drug bioavailability is a major failing point of new pharmaceuticals i.e. drugs fail to reach their target or fail to stay there long enough for therapeutic effect. Compounding this issue, significant variability exists between patients and how they metabolize and distribute a drug. We present WebPK, a web-based tool for simulation of custom pharmacokinetic models. Model parameters can be entered...
January 2009, the forecasting ability of the Delft3D modeling suite was demonstrated in real time for an area in the Northern Gulf of Mexico. As part of the demonstration, a bathyme?trie survey was conducted, and several wave buoys of different types were deployed. Delft3D is a three-dimensional modeling suite that can also be run in depth-averaged mode to provide wave conditions, currents, changes...
Large blackouts are typically caused by cascading failure propagating through a power system by means of a variety of processes. Because of the wide range of time scales, multiple interacting processes, and the huge number of possible interactions, the simulation and analysis of cascading blackouts is extremely complicated. This paper defines cascading failure for blackouts and gives an initial review...
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