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Background: Kawasaki disease (KD) is an acute and systemic vasculitis. Its complications in coronary artery aneurysms (CAA) make KD one of the leading causes of acquired cardiovascular diseases in childhood. Low density lipoprotein receptor-related protein 1B (LRP1B) is abundantly expressed in the medial layer of coronary arteries and involved in endothelium inflammations. Purpose: We aimed to identify...
Kawasaki disease (KD) is a pediatric systemic vasculitis, for which both genetic and environmental factors are suspected. HLA gene clusters within the major histocompatibility complex (MHC) region at chromosome 6p21.3 have been recently linked to KD. However, little was known about the roles of non-MHC genes during KD development. This study examines the association of psoriasis susceptibility 1 (PSORS1)...
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